Introduction: In 1962, a peculiar and unprecedented event occurred in the village of Kashasha, near the western shore of Lake Victoria in Tanganyika (now Tanzania). It started at a mission-run boarding school for girls and rapidly transformed into a widespread phenomenon. This event was the Tanganyika laughing epidemic. In this blog, we delve into the details of this bizarre occurrence, exploring its causes, effects, and implications. The Onset: The incident began in January 1962 when three girls at a boarding school started laughing uncontrollably. This laughter, however, was no sign of amusement; it was involuntary and often accompanied by other symptoms such as crying, fainting, and pain. Remarkably, this peculiar condition started spreading rapidly among the students. The Spread: The epidemic didn't remain confined to the school. As students were sent home to prevent further spread, the condition disseminated across the neighboring communities. In total, 14 schools were shu...